Successful use of recombinant factor VIIa for treatment of severe postpartum hemorrhage.

نویسندگان

  • Ankie E W Hamaekers
  • Walther N K A van Mook
  • J P M Offermans
  • Marco A E Marcus
چکیده

To purchase electronic or print reprints, contact The InnoVision Group, 101 Columbia, Aliso Viejo, CA 92656. Phone, (800) 809-2273 or (949) 362-2050 (ext 532); fax, (949) 362-2049; e-mail, [email protected]. By Ankie E.W. Hamaekers, MD, Walther N.K.A. van Mook, MD, J.P.M. Offermans, MD, PhD, and Marco A.E. Marcus, MD, PhD. From the Departments of Anaesthesiology (AEWH, MAEM), Intensive Care and Internal Medicine (WNVM), and Obstetrics and Gynaecology (JPMO), University Hospital Maastricht, Maastricht, the Netherlands.

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Use of recombinant factor VIIa for massive postpartum haemhorrage: case series and review of literature.

Recombinant activated factor VII is indicated mainly for the treatment of patients with haemophilia inhibitors. It has also been found successful in the treatment of platelet disorder Glanzmann's thrombasthenia. Recently, its use in trauma patients and in patients with intracereberal haemorrhage has become well established. We present three cases of massive post partum haemorrhage treated with ...

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Recombinant human factor VIIa prevents hysterectomy in severe postpartum hemorrhage: single center study.

OBJECTIVE To evaluate the effectiveness of human recombinant activated factor VII (rhFVIIa, NovoSeven) in avoiding hysterectomy postpartum in the management of severe postpartum hemorrhage (PPH). METHODS We performed a prospective cohort study at our university tertiary care center. Patients with severe post partum hemorrhage (blood loss >2000 mL) and failed medical and uterus-preserving surg...

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Recombinant factor VIIa for life-threatening post-partum haemorrhage.

The treatment of life-threatening post-partum haemorrhage (PPH) still remains challenging, and hysterectomy may be required to control the bleeding. We present 12 cases of severe PPH treated with recombinant factor VIIa (rFVIIa). We briefly describe the causes of the haemorrhage and the medical and surgical interventions before rVIIa administration. In 11 women there was a partial or good respo...

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Efficacy and safety of recombinant factor VIIa for treatment of severe bleeding: a systematic review.

BACKGROUND Recombinant activated factor VII (factor VIIa) is a prohemostatic agent that can be used for patients with complicated coagulation disorders. Recombinant factor VIIa is, however, increasingly used for several other indications, including patients with a preexistent normal coagulation system but who experience serious bleeding, for example, after major surgery or trauma. DATA SOURCE...

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عنوان ژورنال:
  • American journal of critical care : an official publication, American Association of Critical-Care Nurses

دوره 15 4  شماره 

صفحات  -

تاریخ انتشار 2006